AAT deficiency (Alpha-1 Antitrypsin deficiency)

Alpha-1 Antitrypsin deficiency (AAT deficiency) is a genetic condition where the body doesn't produce enough of a protein called alpha-1 antitrypsin, which helps protect the lungs and liver from damage. Without enough this protein, the lungs can become inflamed and damaged, leading to conditions like emphysema or chronic obstructive pulmonary disease (COPD). It can also cause liver problems, including cirrhosis. The severity varies; some people experience significant health issues, while others remain relatively unaffected. It is inherited, meaning it runs in families, and can be managed with treatments like supplementation or lifestyle changes to protect lung and liver health.