A20 (TNFAIP3)

A20, also known as TNFAIP3, is a protein that helps regulate the immune system and prevent excessive inflammation. It acts as a brake on immune signals, stopping them from overreacting and causing tissue damage. By controlling inflammation, A20 plays a critical role in maintaining immune balance. Mutations or problems with the A20 gene can lead to immune-related diseases, such as autoimmune disorders, where the body's immune system attacks itself. In summary, A20 is essential for keeping the immune response in check and preventing harmful inflammation.