A-kinase anchoring proteins (AKAPs)

A-kinase anchoring proteins (AKAPs) are specialized proteins that organize and localize signaling molecules within cells. They primarily attach to PKA (protein kinase A), a key enzyme involved in transmitting signals that regulate various cell functions. By anchoring PKA and other signaling components close to their targets, AKAPs ensure precise and efficient communication within the cell. This spatial organization helps cells respond accurately to stimuli, coordinate complex processes like metabolism, growth, and communication, and maintain proper cellular function. In essence, AKAPs act as molecular scaffolds, orchestrating signaling pathways with accuracy and timing.