4DNucleome Project

The 4D Nucleome Project aims to understand how the 3D structure of our DNA inside the cell nucleus changes over time (adding the fourth dimension). By studying this organization, scientists can learn how genes are turned on or off and how misfolded DNA contributes to diseases like cancer. Using advanced imaging and genomic techniques, the project seeks to map the dynamic architecture of the genome, providing insights into fundamental biology and potential avenues for medical breakthroughs. Ultimately, it helps reveal how the spatial and temporal organization of DNA influences health and disease.