3xTg-AD mouse model

The 3xTg-AD mouse model is a genetically engineered laboratory mouse used to study Alzheimer’s disease. It carries three human genes linked to the condition, which lead to the development of key features of Alzheimer’s, such as amyloid plaques and tau tangles in the brain. These mice exhibit memory and learning deficits similar to those seen in humans with Alzheimer’s, making them valuable for researching the disease’s causes and testing potential treatments. The 3xTg-AD model helps scientists understand disease mechanisms and evaluate new interventions in a controlled, biological context.