β2-glycoprotein I

β2-glycoprotein I is a naturally occurring protein in the blood that plays a key role in preventing blood clots and managing immune responses. It helps recognize and clear misplaced or harmful proteins, maintaining blood vessel health. In some autoimmune conditions, like antiphospholipid syndrome, the body develops antibodies against β2-glycoprotein I, which can increase the risk of abnormal blood clotting. Understanding this protein is important for diagnosing and managing such clotting disorders and related autoimmune diseases.