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1918 influenza virus

The 1918 influenza virus, often called the “Spanish flu,” was a highly contagious and severe strain of H1N1 influenza. It spread quickly worldwide, infecting about one-third of the global population and causing an estimated 50 million deaths. Unlike typical flu strains, it affected young adults severely and led to rapid respiratory deterioration. The virus was particularly aggressive due to its ability to evade immune defenses and trigger overactive immune responses. Its impact prompted major public health responses and research, and it highlights the importance of influenza preparedness and vaccination efforts today.