Image for 12. X-linked Agammaglobulinemia (XLA) Related Infections

12. X-linked Agammaglobulinemia (XLA) Related Infections

X-linked Agammaglobulinemia (XLA) is a genetic condition where the body cannot produce enough antibodies, making it difficult to fight off infections. People with XLA are especially vulnerable to infections from bacteria, viruses, and certain fungi, particularly in childhood. Common infections include pneumonia, sinusitis, and skin infections, as well as gastrointestinal issues. Since their immune system lacks adequate defenses, individuals need regular medical care, including antibody replacement therapy, to help prevent and treat infections effectively. Awareness and prompt treatment of infections are crucial for managing health in individuals with XLA.