1. Unclear Etiologies of Pulmonary Hypertension

Unclear etiologies of pulmonary hypertension refer to cases where the cause of high blood pressure in the lungs remains unknown. This condition means that the blood vessels in the lungs are narrowed or blocked, making it harder for blood to flow and leading to strain on the heart. While some causes are well understood, like heart disease or lung issues, other cases cannot be easily linked to any specific factor. This uncertainty makes diagnosis and treatment challenging, necessitating ongoing research to better understand the underlying mechanisms and develop effective therapies.